Juniper Publishers- Journal of Pharmacy Pharmaceutical Sciences

   JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Rambabu C Abstract Two sensitive and accurate extractive spectrophometric methods have been developed for the estimation of dothiepin in pure and pharmaceutical dosage forms. The developed methods are based on the formation of colored solvent extractible ion-association complexes of the drug with bromocresol blue [BCB] and eriochrome black-T [EBT]. The extracted complexes showed absorbance maxima at 418 and 508 nm respectively. Beer's law is obeyed in the concentration ranges between 16 - 56 and 5-17.5μ/mL for the two methods respectively. The effective concentration of dye, pH and optimum conditions are established for these methods. The methods are applied for the determination of the drug in commercial tablets and results of analysis are validated statistically through recovery studies. Keywords:  Dothiepin; Spectrophotometric methods; BCB; EBT; Dichloromethane; Chloroform Go to Introduc

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Kala C Abstract The immunomodulatory potential of methanolic extract of leave extract of  Drypetes roxburghii  leaves was evaluated. For this models like estimation of serum Immunoglobulin level and carbon clearance test were used All the Data was analyzed by one way ANOVA followed by Dunnet's test at *p<0.05, **p<0.01, ***p<0.001. Serum immunoglobulin level was raised from normal 61.4±1.47 NTU up to 69.083±1.549** and 101.416±1.367*** NTU in Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. Phagocytic index of animals in control group was found to be 1.8±0.186 and was raised up to 2.98±0.069 ns  and 3.97±0.690** Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. This study showed that methanolic extract of  Drypetes roxburghii  leaves possessed immunostimulat

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Roy H Abstract Polymers assume a noteworthy part in the improvement of medication conveyance innovation by arrival of two sorts of medications like hydrophilic and hydrophobic. In a synchronized way and consistent arrival of plans over broadened periods. There are various favorable circumstances of polymers going about as a dormant transporter. Nonetheless they have their own particular impediments, for example, the polymers regularly delivers undesirable and undesirable symptom, immunogenic enactment potential, should have been surgery after they discharge the medication at the focused in the vicinity and cost additionally a potential element. In such respects, Natural polymers turned out to be the better option limiting the risk of disappointment of medication conveyance framework. Keywords:  Polymers; Hydrophillic; Natural; Immunogenic Go to Introduction Polymers are substances whose particle