Juniper Publishers- Journal of Pharmacy Pharmaceutical Sciences

JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Nasal delivery of protein/peptide drugs has gained considerable amount of attention over the past decade, since it has several advantages over the oral delivery as it avoids harsh gastrointestinal environment, has relatively less enzymatic degradation and relatively highly permeable epithelial mucosa. Nasal products of several small molecular weight (MW < 4000Da) protein/peptide drugs have been approved by the US FDA. This review is focused on the challenges associated with nasal delivery of protein/peptide drugs and possible solutions through various drug delivery technologies. Keywords : Nasal absorption; Intranasal delivery; Proteins; Peptides; Nasal mucosa Introduction Recent years have shown that nasal route can be a potential route for the systemic delivery of protein/peptide drugs as it has a considerably large absorptio...

JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES The behavior of employees is influenced by the environment in which they find themselves and dissatisfaction associated with bad working conditions account for employees’ new job searches and actual separations. The objectives of this study were to examine the relationship between work content and motivation, on one hand, and work context and motivation, on the other hand, of hospital pharmacists in Osun state of Nigeria. Eighty seven out of 110 practicing pharmacists in secondary and tertiary hospitals in Osun State were selected randomly. They were then interviewed with the aid of a set of pre-tested semi-structured questionnaire that comprised two sections. The main section employed thirty three items made of statements on a Likert-type scale to elicit information on the relationship between work content, work context and motivation of the respondents. Descriptive statistics ...

  JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Salivary nitrite is derived from salivary nitrate that obtained from ingested nitrate since 25% of nitrate is secreted through saliva thus; salivary nitrate is 10-20 times higher than plasma nitrate. Nitrate-nitric-NO pathway plays a role in prevention of insulin resistance and progression of diabetes mellitus. Because of salivary nitrite is also generated from NO metabolism therefore, salivary nitrite may reflect the endogenous NO production and endothelial function in various diseases thus; the aim of present study was evaluation of salivary nitrite in controlled and complicated T2DM regarding the current diabetic pharmacotherapy. In this study a total number of 50 patients with T2DM were selected randomly compared with 27 healthy subjects. 10ml of venous blood from all patients and healthy subjects after an overnight fasting was drawn, lipid profile, fasting blood gluc...

Juniper Publishers Contact Number Phone: +1-805-200-4030 https://g.page/Juniper_Publishers?share

Juniper Publishers Contact Info Phone: +1-805-200-4030 Fax: 1-855-420-6872 Email:  info@juniperpublishers.com Web :  www.juniperpublishers.com

Juniper Publishers Address 427 W Duarte Rd, Suite E, Arcadia, California, CA 91007 United States https://juniperpublishers.com/contact-us.php