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A Review on the Safety of Inhalation of Propylene Glycol in E-cigarettes _Juniper Publishers

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JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Cotta KI Abstract Electronic cigarette (e-cigarette) are being used as a safe alternative to tobacco smoking, or as a smoking cessation device. However, the FDA presumes that e-cigarettes are as hazardous as conventional cigarettes. The Tobacco Control Task Force of the American Association of Public Health Physicians instead has indicated that e-cigarettes closely resemble Nicotine Replacement Therapy products. Since Propylene glycol (PG) constitutes around 89-90% of the e-cigarettes formulation, the objective here is to review the safety of inhalation of PG. All animal and human studies that analyzed the effect of the inhalation of PG have indicated that, PG does not appear to pose a significant hazard via the inhalation route. In fact, in several of these animal studies the concentrations of PG used were higher compared to the concentration used in e-cigarettes and did not give rise to any toxi...

Immunomodulatory Activity of Methanolic Extract of Drypetes Roxburghii Leaves - Juniper Publishers

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  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Kala C Abstract The immunomodulatory potential of methanolic extract of leave extract of  Drypetes roxburghii  leaves was evaluated. For this models like estimation of serum Immunoglobulin level and carbon clearance test were used All the Data was analyzed by one way ANOVA followed by Dunnet's test at *p<0.05, **p<0.01, ***p<0.001. Serum immunoglobulin level was raised from normal 61.4±1.47 NTU up to 69.083±1.549** and 101.416±1.367*** NTU in Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. Phagocytic index of animals in control group was found to be 1.8±0.186 and was raised up to 2.98±0.069 ns  and 3.97±0.690** Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. This study showed that methanolic extract of  Drypetes roxburghii  leaves...

Polymers of Natural Origin in Advanced Study of Research: Fabrication of Pharmaceutical Delivery Device - Juniper Publishers

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  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Roy H Abstract Polymers assume a noteworthy part in the improvement of medication conveyance innovation by arrival of two sorts of medications like hydrophilic and hydrophobic. In a synchronized way and consistent arrival of plans over broadened periods. There are various favorable circumstances of polymers going about as a dormant transporter. Nonetheless they have their own particular impediments, for example, the polymers regularly delivers undesirable and undesirable symptom, immunogenic enactment potential, should have been surgery after they discharge the medication at the focused in the vicinity and cost additionally a potential element. In such respects, Natural polymers turned out to be the better option limiting the risk of disappointment of medication conveyance framework. Keywords:  Polymers; Hydrophillic; Natural; Immunogenic Go to Introduction Polymers are substances whose...