Juniper Publishers- Journal of Pharmacy Pharmaceutical Sciences

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Roy H Abstract Polymers assume a noteworthy part in the improvement of medication conveyance innovation by arrival of two sorts of medications like hydrophilic and hydrophobic. In a synchronized way and consistent arrival of plans over broadened periods. There are various favorable circumstances of polymers going about as a dormant transporter. Nonetheless they have their own particular impediments, for example, the polymers regularly delivers undesirable and undesirable symptom, immunogenic enactment potential, should have been surgery after they discharge the medication at the focused in the vicinity and cost additionally a potential element. In such respects, Natural polymers turned out to be the better option limiting the risk of disappointment of medication conveyance framework. Keywords:  Polymers; Hydrophillic; Natural; Immunogenic Go to Introduction Polymers are substances whose...

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Tsikas D Abstract Spermidine, N-(3-aminopropyl) butane-1,4-diamine, is an endogenous basic compound known for more than 90 years. The biosynthesis of spermidine, its pharmacological properties including distribution, metabolism and excretion have been thoroughly investigated. Spermidine and other polyamines have been early associated with growth and aging, and were found to stabilize various cellular and subcellular components including nucleic acids due to their polyvalent cationic structures. Polyamines including spermidine have been found at elevated circulating and urinary concentrations in a variety of diseases including cancer and psoriasis. Thus, decreasing the concentration of polyamines mainly by inhibiting their biosynthesis is regarded as a realistic therapeutical strategy. Yet, more recent studies suggest that exogenous spermidine exerts beneficial effects on th...