Juniper Publishers- Journal of Pharmacy Pharmaceutical Sciences

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Kala C Abstract The immunomodulatory potential of methanolic extract of leave extract of  Drypetes roxburghii  leaves was evaluated. For this models like estimation of serum Immunoglobulin level and carbon clearance test were used All the Data was analyzed by one way ANOVA followed by Dunnet's test at *p<0.05, **p<0.01, ***p<0.001. Serum immunoglobulin level was raised from normal 61.4±1.47 NTU up to 69.083±1.549** and 101.416±1.367*** NTU in Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. Phagocytic index of animals in control group was found to be 1.8±0.186 and was raised up to 2.98±0.069 ns  and 3.97±0.690** Drypetes roxbhrghii low dose (DHLD) (100mg/kg) and Drypetes roxbhrghii high dose (DRHD) (200mg/kg) respectively. This study showed that methanolic extract of  Drypetes roxburghii  leaves...

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Authored by Roy H Abstract Polymers assume a noteworthy part in the improvement of medication conveyance innovation by arrival of two sorts of medications like hydrophilic and hydrophobic. In a synchronized way and consistent arrival of plans over broadened periods. There are various favorable circumstances of polymers going about as a dormant transporter. Nonetheless they have their own particular impediments, for example, the polymers regularly delivers undesirable and undesirable symptom, immunogenic enactment potential, should have been surgery after they discharge the medication at the focused in the vicinity and cost additionally a potential element. In such respects, Natural polymers turned out to be the better option limiting the risk of disappointment of medication conveyance framework. Keywords:  Polymers; Hydrophillic; Natural; Immunogenic Go to Introduction Polymers are substances whose...

  JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES   Authored by Kansal D Abstract Introduction: Prescription audit is necessary to know the prescription practices and to improve rational pharmacotherapy. In India few publications are available on prescription audit. Materials and method: This was an observational study, undertaken between August 2016 to October 2016 for which data was collected from our OPDs. Results were compiled, tabulated and analyzed using Microsoft excel. Charts were drawn to present all the findings. Results: In total 317 medications were prescribed in 113 prescription notes. Therefore average number of drugs/prescription was 2.80. Demographic profile shows more females (58.40%) as compared to males (41.60%). Maximum patients (73.45%) were from adult age group, followed by children (14.15%). Most common dosage form was oral in 83.59%, topical were prescribed in 9.14% and injectable were recommended in 7.25...

JUNIPER PUBLISHERS - GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES   Authored by Eerike M Abstract Chronic hyperglycemia in diabetes will produce microvascualr & macrovascular complications. Strict glycemic control can reduce but not completely prevent the microvascular complications. C-peptide, a connecting peptide is one of the drugs under clinical trials for treatment of diabetic complications. Previously C-peptide was considered as a byproduct of insulin synthesis, but now it has been proven, as an active hormone with various actions. Replacement with C-peptide has been proven to reduce the type-1 diabetic complications but not in type 2 diabetic complications. This review is focusing on mechanism of action and actions of C-peptide, its role in type1 & type 2 diabetic complications, clinical trials related to C-peptide has been discussed. Keywords: Hyperglycemia; Microvascular complications; C-peptide; Diabetes; Clinical trial Abbreviati...