Juniper Publishers- Journal of Pharmacy Pharmaceutical Sciences

Juniper Publishers-Open Access Journal of Pharmacy & Pharmaceutical Sciences Authored by  Prasanthi T A simple, precise, rapid and accurate UV Spectrophotometric method has been developed and validated for the simultaneous estimation of Omeprazole (OMP) and Domperidone (DOM) in combined pharmaceutical dosage forms. The method was developed by using methanol as a solvent. Omeprazole exhibits absorption maximum at 301 nm and Domperidone shows absorption maximum at 287.2 nm in methanol. The developed method was obeyed Beer Lambert’s law in the concentration range of 2-12 μg/mL for both OMP and DOM. The accuracy of method was confirmed by recovery studies from capsules at three different levels of standard additions. %RSD values below 2 for intra-day and inter-day precision indicates that the proposed method is highly reproducible. The results of study demonstrated that the proposed method can be applied to formulation and for routine analysis. To view more...  Pharmacy

Juniper Publishers-Open Access Journal of Pharmacy & Pharmaceutical Sciences Authored by  Ranasinghe RLDS Macrotyloma uniflorum  (Lam.) Verdc commonly known as horse gram is a kind of legume of tropics and subtropics. Its medicinal uses are known to Ayurveda and Sri Lankan traditional physicians for centuries. Present study was undertaken to collect data on medicinal uses and nutritional values of  M. uniflorum . Ayurveda pharmacodynamic properties of  M. uniflorum  are  Kashaya Rasa, Laghu, Ruksha, Tikshna Guna, Ushna Veerya and Katu Vipaka.  Various medicinal preparations such as Dhanyamla and decoctions are prepared using seeds of  M. uniflorum.  It is mainly used as a tonic, astringent, diuretic and also recommended in rheumatism, neuralgia and other several diseases. Horse gram seeds are rich in natural phenols; mostly phenolic acids, flavonoids and the major anti-oxidants. Horse gram is considered as animal fodder and its full potential as a part of human diet has