Juniper Publishers: A Critical Analysis of Polymersome Therapeutics: F...

Juniper Publishers: A Critical Analysis of Polymersome Therapeutics: F...: Current Trends in Biomedical Engineering & Biosciences Juniper Publishers Authored by  Adriano Marim de Oliveira * Introdu...

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Effect of Vitamin E on the Anti-Coagulant Response-Juniper Publishers

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JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Fluindione is the most used Vitamin K antagonists in France. It has been sparsely studied and few interactions have been reported with food sources. This case reveals a significant rise in INR when fluindione was associated to fatty acid (palmitic/oleic/linoleic acid 2g/day) or vitamin E (1g/day). Presentation of Case: A 80-year-old male (weight 74 kg, body surface area 1.91 m²) with a history of severe allergic drug eruption documented with low molecular weight heparins, vancomycin, rifamycin and netromycin was treated and stabilized (International Normalized Ratio (INR) = 3.5) with fluindione (10 to 15 mg once per day) for cardiovascular risks due to a mechanical aortic heart valve and an aortic tube. During hospitalization, the patient stopped eating dietary supplements containing fatty acids and vitamin E (Day 0), and then, presented an imbalance of the INR (Day 2: INR =...
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Formulation and Evaluation of Solid Dispersion of Glimepiride into Sustained Release-Juniper Publishers

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JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES A sustained release tablet containing Glimepiride was formulated by using solid dispersion technique. Solid dispersions of glimepiride were prepared by using Urea and PEG 6000 as carrier in drug: carrier 1:1, 1:2, 1:3, 1:4 ratios by Fusion method. From these all solid dispersions formulation SDUF3 containing Urea shows better dissolution compared to other solid dispersions. This optimized solid dispersion is formulated into sustained release tablets by direct compression method using hydroxy propyl methyl cellulose and Ethyl cellulose polymers. Keywords: Solid dispersion, Diabetes mellitus, Sustained drug release Abbreviations: PVP: Poly Vinyl Pyrrolidone; HPMC: Hydroxy Propyl Methyl Cellulose; FTIR: Fourier Transform Infra Red; MCC: Micro Crystalline Cellulose Introduction The objective of sustained release [1] dosage form i...
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Medicinal and Nutritional Values of Macrotyloma uniflorum (Lam.) Verdc (Kulattha): A Conceptual Study-Juniper publishers

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JUNIPER PUBLISHERS-OPEN ACCESS GLOBAL JOURNAL OF PHARMACY & PHARMACEUTICAL SCIENCES Macrotyloma uniflorum (Lam.) Verdc commonly known as horse gram is a kind of legume of tropics and subtropics. Its medicinal uses are known to Ayurveda and Sri Lankan traditional physicians for centuries. Present study was undertaken to collect data on medicinal uses and nutritional values of M. uniflorum . Ayurveda pharmacodynamic properties of M. uniflorum are Kashaya Rasa, Laghu, Ruksha, Tikshna Guna, Ushna Veerya and Katu Vipaka. Various medicinal preparations such as Dhanyamla and decoctions are prepared using seeds of M. uniflorum. It is mainly used as a tonic, astringent, diuretic and also recommended in rheumatism, neuralgia and other several diseases. Horse gram seeds are rich in natural phenols; mostly phenolic acids, flavonoids and the major anti-oxidants. Horse gram is considered as animal fodder and its full potential as a part of human diet has not been exploited ...
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