JuniperPublishers-Global Journal of Pharmacy & Pharmaceutical Sciences

Juniper Publishers-Open Access Journal of Pharmacy & Pharmaceutical Sciences

Curcumin: A Multiple Edged Sword in the Prevention of Cancer

Authored by Anmol Goyal

Cancer is a major public health problem and is accompanied by gradual accumulation of epigenetic and genetic alterations that disturbs cellular homeostasis. The current approach for the treatment of cancer is potentially based on the use of chemotherapeutic agents. Despite significant advances in the therapeutic modalities, these anti neoplastic drugs exert low therapeutic response, associated with side effects and are also expensive. Thus, there is urgent necessity of pharmacological agents which may attenuate anticancer agents associated disadvantages. Curcumin, a polyphenolic compound is one such natural remedy which is potentially qualified as a multiple edged sword due to its broad biological activity. Earlier studies have reported that curcumin acts as an anti-inflammatory, anti-proliferative and anti-metastatic agent without showing any deleterious effects. The current review summarizes the understanding the role of curcumin as a potential drug to control the development and progression of cancer.

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